International Journal of Pediatric Otorhinolaryngology
Volume 74, Issue 8 , Pages 913-919 , August 2010

Cisplatinum ototoxicity in children, long-term follow up

  • Talal Al-Khatib

      Affiliations

    • Department of Otolaryngology-Head and Neck Surgery, McGill University, Montreal, Canada
    • Corresponding Author InformationCorresponding author at: The Montreal Children's Hospital, McGill University Health Centre, 2300 Tupper St., Montreal, QC H3H 1P3, Canada. Tel.: +1 514 412 4304/4303; fax: +1 514 412 4342.
  • ,
  • Natasha Cohen

      Affiliations

    • Department of Otolaryngology-Head and Neck Surgery, McGill University, Montreal, Canada
  • ,
  • Anne-Sophie Carret

      Affiliations

    • Department of Hematology/Oncology, Montreal's Children Hospital, Montreal, Canada
  • ,
  • Sam Daniel

      Affiliations

    • Department of Otolaryngology-Head and Neck Surgery, McGill University, Montreal, Canada

Received 28 February 2010 ,Revised 6 May 2010 ,Accepted 9 May 2010.

References 

  1. Clark JG. Uses and abuses of hearing loss classification. ASHA. 1981;23:493–500
  2. Lewis MJ, DuBois SG, Fligor B, Li X, Goorin A, Grier HE. Ototoxicity in children treated for osteosarcoma. Pediatr. Blood Cancer. 2009;52:387–391
  3. Schell MJ, McHaney VA, Green AA. Hearing loss in children and young adults receiving cisplatin with or without prior cranial irradiation. J. Clin. Oncol. 1989;7:754–760
  4. Coradini PP, Cigana L, Selistre SG, Rosito LS, Brunetto AL. Ototoxicity from cisplatin therapy in childhood cancer. J. Pediatr. Hematol. Oncol. 2007;29:355–360
  5. Dean JB, Hayashi SS, Albert CM, King AA, Karzon R, Hayashi RJ. Hearing loss in pediatric oncology patients receiving carboplatin-containing regimens. J. Pediatr. Hematol. Oncol. 2008;30:130–134
  6. Fouladi M, Gururangan S, Moghrabi A. Carboplatin-based primary chemotherapy for infants and young children with CNS tumors. Cancer. 2009;115:3243–3253
  7. Knight KR, Kraemer DF, Neuwelt EA. Ototoxicity in children receiving platinum chemotherapy: underestimating a commonly occurring toxicity that may influence academic and social development. J. Clin. Oncol. 2005;23:8588–8596
  8. Bertolini P, Lassalle M, Mercier G. Platinum compound-related ototoxicity in children: long-term follow-up reveals continuous worsening of hearing loss. J. Pediatr. Hematol. Oncol. 2004;26:649–655
  9. Stelmachowicz PG, Pittman AL, Hoover BM, Lewis DE, Moeller MP. The importance of high-frequency audibility in the speech and language development of children with hearing loss. Arch. Otolaryngol. Head Neck Surg. 2004;130:556–562
  10. Stelmachowicz PG, Pittman AL, Hoover BM, Lewis DE. Effect of stimulus bandwidth on the perception of/s/in normal- and hearing-impaired children and adults. J. Acoust. Soc. Am. 2001;110:2183–2190
  11. Martinez-Cruz CF, Poblano A, Conde-Reyes MP. Cognitive performance of school children with unilateral sensorineural hearing loss. Arch. Med. Res. 2009;40:374–379
  12. Culbertson JL, Gilbert LE. Children with unilateral sensorineural hearing loss: cognitive, academic, and social development. Ear Hear. 1986;7:38–42
  13. Durrant . SAFMTJWKRBSMFKSHVAMJMTJ. Guidelines for the audiologic management of individuals receiving cochleotoxic drug therapy. ASHA. 1994;36:11
  14. Beck MN, Balmer A, Dessing C, Pica A, Munier F. First-line chemotherapy with local treatment can prevent external-beam irradiation and enucleation in low-stage intraocular retinoblastoma. J. Clin. Oncol. 2000;18:2881–2887
  15. Yoshinaga-Itano C, Sedey AL, Coulter DK, Mehl AL. Language of early- and later-identified children with hearing loss. Pediatrics. 1998;102:1161–1171
  16. Rybak LP, Whitworth CA, Mukherjea D, Ramkumar V. Mechanisms of cisplatin-induced ototoxicity and prevention. Hear. Res. 2007;226:157–167
  17. van Ruijven MW, de Groot JC, Hendriksen F, Smoorenburg GF. Immunohistochemical detection of platinated DNA in the cochlea of cisplatin-treated guinea pigs. Hear. Res. 2005;203:112–121
  18. Meech RP, Campbell KC, Hughes LP, Rybak LP. A semiquantitative analysis of the effects of cisplatin on the rat stria vascularis. Hear. Res. 1998;124:44–59
  19. Alam SA, Ikeda K, Oshima T. Cisplatin-induced apoptotic cell death in Mongolian gerbil cochlea. Hear. Res. 2000;141:28–38
  20. Liang F, Schulte BA, Qu C, Hu W, Shen Z. Inhibition of the calcium- and voltage-dependent big conductance potassium channel ameliorates cisplatin-induced apoptosis in spiral ligament fibrocytes of the cochlea. Neuroscience. 2005;135:263–271
  21. Husain K, Scott RB, Whitworth C, Somani SM, Rybak LP. Dose response of carboplatin-induced hearing loss in rats: antioxidant defense system. Hear. Res. 2001;151:71–78
  22. Garcia-Ruiz C, Colell A, Mari M, Morales A, Fernandez-Checa JC. Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. Role of mitochondrial glutathione. J. Biol. Chem. 1997;272:11369–11377
  23. Li Y, Womer RB, Silber JH. Predicting cisplatin ototoxicity in children: the influence of age and the cumulative dose. Eur. J. Cancer. 2004;40:2445–2451
  24. Ruiz L, Gilden J, Jaffe N, Robertson R, Wang YM. Auditory function in pediatric osteosarcoma patients treated with multiple doses of cis-diamminedichloroplatinum(II). Cancer Res. 1989;49:742–744
  25. Brock PR, Bellman SC, Yeomans EC, Pinkerton CR, Pritchard J. Cisplatin ototoxicity in children: a practical grading system. Med. Pediatr. Oncol. 1991;19:295–300
  26. Ilveskoski I, Saarinen UM, Wiklund T. Ototoxicity in children with malignant brain tumors treated with the “8 in 1” chemotherapy protocol. Med. Pediatr. Oncol. 1996;27:26–31
  27. Chen WC, Jackson A, Budnick AS. Sensorineural hearing loss in combined modality treatment of nasopharyngeal carcinoma. Cancer. 2006;106:820–829
  28. Walker DA, Pillow J, Waters KD, Keir E. Enhanced cis-platinum ototoxicity in children with brain tumours who have received simultaneous or prior cranial irradiation. Med. Pediatr. Oncol. 1989;17:48–52
  29. Boothroyd A. Room acoustics and speech perception. Semin. Hear. 2002;18
  30. Horwitz AR, Dubno JR, Ahlstrom JB. Recognition of low-pass-filtered consonants in noise with normal and impaired high-frequency hearing. J. Acoust. Soc. Am. 2002;111:409–416
  31. Eisenberg LS, Shannon RV, Martinez AS, Wygonski J, Boothroyd A. Speech recognition with reduced spectral cues as a function of age. J. Acoust. Soc. Am. 2000;107:2704–2710
  32. Bess FH, Dodd-Murphy J, Parker RA. Children with minimal sensorineural hearing loss: prevalence, educational performance, and functional status. Ear Hear. 1998;19:339–354
  33. Furstenberg K, Doyal G. The relationship between emotional-behavioral functioning and personal characteristics on performance outcomes of hearing impaired students. Am. Ann. Deaf. 1994;139:410–414

PII: S0165-5876(10)00221-1

doi: 10.1016/j.ijporl.2010.05.011

International Journal of Pediatric Otorhinolaryngology
Volume 74, Issue 8 , Pages 913-919 , August 2010