International Journal of Pediatric Otorhinolaryngology
Volume 74, Issue 4 , Pages 369-373, April 2010

Bupivacaine versus normal saline for relief of post-adenotonsillectomy pain in children: A meta-analysis

  • Jiehao Sun

      Affiliations

    • Department of Anesthesiology, 1st Affiliated Hospital, Wenzhou Medical College, Wenzhou, China
    • Corresponding Author InformationCorresponding author. Tel.: +86 13676721930.
    • ,
  • Xiuying Wu

      Affiliations

    • Department of Anesthesiology, Shengjing Hospital, China Medical University, Shenyang, China
    • ,
  • Yinan Meng

      Affiliations

    • Department of Anesthesiology, 1st Affiliated Hospital, Wenzhou Medical College, Wenzhou, China
    • ,
  • Lielie Jin

      Affiliations

    • Department of Anesthesiology, 1st Affiliated Hospital, Wenzhou Medical College, Wenzhou, China

Received 4 October 2009; received in revised form 1 January 2010; accepted 9 January 2010.

Abstract 

Objective

A meta-analysis was performed to explore the role of peri-operative bupivacaine infiltration in the relief of pain in adenotonsillectomy.

Methods

Data from Medline, EMBase, Springer and the Cochrane Collaboration database were searched. Reference lists from identified publications were scanned. RevMan 5.0 software was used for statistical analysis.

Results

7 random controlled tests (a total of 286 cases) were included. Pain intensity was evaluated by VAS score or Cheops score. The pain of group bupivacaine (Group B) was less severe than group placebo (Group P). Analgesic requirement of Group B was less than Group P. Nevertheless the difference of complication between bupivacaine and placebo had no statistical difference.

Conclusion

Bupivacaine infiltration is a safe and effective method for relief of pediatric post-adenotonsillectomy pain.

Keywords: Bupivacaine, Adenotonsillectomy, Meta-analysis

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PII: S0165-5876(10)00007-8

doi:10.1016/j.ijporl.2010.01.004

International Journal of Pediatric Otorhinolaryngology
Volume 74, Issue 4 , Pages 369-373, April 2010

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