International Journal of Pediatric Otorhinolaryngology
Volume 67, Issue 4 , Pages 409-412, April 2003

Hyper immunoglobulin-E syndrome: a case with chronic ear draining mimicking polypoid otitis media

Fatih mah, Babil cad, Girne sitesi, D. blok, No: 1/1. 33170 Mezitli, Mersin, Turkey

Received 18 August 2002; received in revised form 4 November 2002; accepted 6 November 2002.

Abstract 

The hyper-IgE syndrome is a rare, complex immunoregulatory disorder characterized by pruritic dermatitis, recurrent staphylococcus skin abscesses and extremely elevated levels of IgE in serum. In this report, an 8-year-old girl with hyper-IgE syndrome is presented. She had pruritic dermatitis and skin abscesses on her extremities and scalp. Discharge and granulation tissue in right external ear canal were recognized in otorhinolaryngologic examination. Cultures of the suppuration of the external ear canal yielded S. aureus. Biopsy of the lesion was reported as granulation tissue. Local treatment of the ear canal was performed with ear wick soaked with steroid and antibiotic solutions two times per day.

Keywords: Job syndrome, Hyperimmunoglobulin E, Dermatitis, IL-12, Chemokines

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PII: S0165-5876(02)00390-7

doi:10.1016/S0165-5876(02)00390-7

International Journal of Pediatric Otorhinolaryngology
Volume 67, Issue 4 , Pages 409-412, April 2003

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